Pterostilbene
What is Pterostilbene?
Pterostilbene is a natural compound found in many fruits. It is structurally similar to resveratrol, another antioxidant found in red wine. Pterostilbene is known for its potent antioxidant and anti-inflammatory properties, and it is used to support cardiovascular health, cognitive function, and longevity.
What are the Benefits of Pterostilbene?
Antioxidant: Pterostilbene protects cells from oxidative damage by neutralizing free radicals.
Anti-inflammatory: It reduces inflammation and supports overall health, particularly in conditions like cardiovascular disease and metabolic syndrome.
Cognitive Function: Pterostilbene may improve brain health and cognitive function, potentially reducing the risk of neurodegenerative diseases.
What Research is on Pterostilbene?
Research on pterostilbene includes:
- Cancer Prevention: Studies show that pterostilbene has potential anti-cancer properties, including inhibiting cancer cell growth and inducing apoptosis.
- Cognitive Health: Research suggests that pterostilbene can improve cognitive function, protect against neurodegenerative diseases, and enhance brain health.
- Cardiovascular Health: Pterostilbene has been shown to improve heart health by reducing oxidative stress, lowering blood pressure, and improving lipid profiles.
What is the Mechanism of Action for Pterostilbene?
Antioxidant Activity: Pterostilbene neutralizes free radicals and reduces oxidative damage to cells.
Gene Expression Modulation: It influences genes involved in inflammation, metabolism, and cell cycle regulation, providing protective effects against various diseases.
Lipid Metabolism: Pterostilbene improves lipid metabolism, reducing cholesterol levels and supporting cardiovascular health.
What is the Typical Dosage of Pterostilbene?
Typical dosages of pterostilbene range from 50-150 mg per day. It is often combined with other antioxidants like resveratrol to enhance its effects.
What Foods are Rich in Pterostilbene?
Pterostilbene is found in:
- Blueberries: The richest natural source of pterostilbene.
- Grapes: Contain moderate amounts of pterostilbene.
- Peanuts: Also a source of this compound, though in smaller quantities.
Qu, Xin et al. “Pterostilbene as a Therapeutic Alternative for Central Nervous System Disorders: A Review of the Current Status and Perspectives.” Journal of agricultural and food chemistry vol. 71,40 (2023): 14432-14457. doi:10.1021/acs.jafc.3c06238
Özyalçın, Büşra, and Nevin Sanlier. “Antiobesity pathways of pterostilbene and resveratrol: a comprehensive insight.” Critical reviews in food science and nutrition, 1-9. 24 Jul. 2023, doi:10.1080/10408398.2023.2238319